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Expert Data - Assisted Diagnosis: An INFO - iTransformer - XGBoost Combined Discriminative System for Prenatal Diagnosis of Fetal Congenital Heart Disease

  • Beihang University
  • Capital Medical University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In prenatal screening for fetal congenital heart disease (CHD), ultrasonic diagnosis and other methods are prone to being affected by regional resource differences and insufficient experience in diagnosing doctors, thus resulting in misdiagnosis of cases. This research puts forward a combined discriminative system, which integrates the iTransformer method and XGBoost to aid in the prenatal diagnosis of fetal CHD. This system, named INFO-iTransformer-XGBoost, merges a combined discriminative system, INFO (Weighted mean of vectors optimization algorithm), and SHAP (SHapley Additive exPlanations) explainable analysis prediction model. By comparing the model results with those from INFO-iTransformer and INFO-XGBoost alone, the study confirms the advantage of the combined discriminative system in prenatal CHD screening for fetuses. The study used the fetal CHD detection dataset provided by the Maternal and Fetal Medicine Center of Beijing Anzhen Hospital, Capital Medical University, from February 2018 to August 2024. The research shows that the INFO-iTransformer-XGBoost combined discriminative system and SHAP model explainability analysis can provide a quantitative diagnosis and clinically interpretable diagnostic solution for prenatal CHD screening.

Original languageEnglish
Title of host publicationKnowledge Science, Engineering and Management - 18th International Conference, KSEM 2025, Proceedings
EditorsTianqing Zhu, Wanlei Zhou, Congcong Zhu
PublisherSpringer Science and Business Media Deutschland GmbH
Pages291-298
Number of pages8
ISBN (Print)9789819530571
DOIs
StatePublished - 2026
Event18th International Conference on Knowledge Science, Engineering and Management, KSEM 2025 - Macao, China
Duration: 4 Aug 20257 Aug 2025

Publication series

NameLecture Notes in Computer Science
Volume15922 LNAI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference18th International Conference on Knowledge Science, Engineering and Management, KSEM 2025
Country/TerritoryChina
CityMacao
Period4/08/257/08/25

Keywords

  • Combined Discriminative System
  • Fetal congenital heart disease prediction
  • SHAP explainability analysis

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