Enhancing SERS detection on a biocompatible metallic substrate for diabetes diagnosing

Zhiquan Cui; Libin Lu; Yingchun Guan; Seeram Ramakrishna; Minghui Hong

doi:10.1364/OL.430044

Enhancing SERS detection on a biocompatible metallic substrate for diabetes diagnosing

Zhiquan Cui
, Libin Lu
, Yingchun Guan^*
, Seeram Ramakrishna
, Minghui Hong

^*Corresponding author for this work

School of Mechanical Engineering and Automation

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

A method to realize surface-enhanced Raman spectroscopy (SERS) at a titanium alloy substrate for glucose detection has been experimentally demonstrated. A silver-coated laser-induced periodic surface structure (LIPSS) was prepared via femtosecond laser micro-processing. The low detection limit of glucose is 10^-7 mol/L and, a good linear relationship between the glucose concentration and Raman intensity is found in the range between 1 × 10^-7 and 1 × 10^-3 mol/L. Moreover, we investigate SERS detection for glucose sensing in human urine samples, while the results are in good agreement with clinical results. The Letter provides a facile method for producing a structure-controlled SERS substrate to realize glucose detection, which is promising for long-term in vivo diagnostics.

Original language	English
Pages (from-to)	3801-3804
Number of pages	4
Journal	Optics Letters
Volume	46
Issue number	15
DOIs	https://doi.org/10.1364/OL.430044
State	Published - 1 Aug 2021

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title = "Enhancing SERS detection on a biocompatible metallic substrate for diabetes diagnosing",

abstract = "A method to realize surface-enhanced Raman spectroscopy (SERS) at a titanium alloy substrate for glucose detection has been experimentally demonstrated. A silver-coated laser-induced periodic surface structure (LIPSS) was prepared via femtosecond laser micro-processing. The low detection limit of glucose is 10-7 mol/L and, a good linear relationship between the glucose concentration and Raman intensity is found in the range between 1 × 10-7 and 1 × 10-3 mol/L. Moreover, we investigate SERS detection for glucose sensing in human urine samples, while the results are in good agreement with clinical results. The Letter provides a facile method for producing a structure-controlled SERS substrate to realize glucose detection, which is promising for long-term in vivo diagnostics.",

author = "Zhiquan Cui and Libin Lu and Yingchun Guan and Seeram Ramakrishna and Minghui Hong",

note = "Publisher Copyright: {\textcopyright} 2021 Optical Society of America.",

year = "2021",

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day = "1",

doi = "10.1364/OL.430044",

language = "英语",

volume = "46",

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T1 - Enhancing SERS detection on a biocompatible metallic substrate for diabetes diagnosing

AU - Cui, Zhiquan

AU - Lu, Libin

AU - Guan, Yingchun

AU - Ramakrishna, Seeram

AU - Hong, Minghui

PY - 2021/8/1

Y1 - 2021/8/1

N2 - A method to realize surface-enhanced Raman spectroscopy (SERS) at a titanium alloy substrate for glucose detection has been experimentally demonstrated. A silver-coated laser-induced periodic surface structure (LIPSS) was prepared via femtosecond laser micro-processing. The low detection limit of glucose is 10-7 mol/L and, a good linear relationship between the glucose concentration and Raman intensity is found in the range between 1 × 10-7 and 1 × 10-3 mol/L. Moreover, we investigate SERS detection for glucose sensing in human urine samples, while the results are in good agreement with clinical results. The Letter provides a facile method for producing a structure-controlled SERS substrate to realize glucose detection, which is promising for long-term in vivo diagnostics.

AB - A method to realize surface-enhanced Raman spectroscopy (SERS) at a titanium alloy substrate for glucose detection has been experimentally demonstrated. A silver-coated laser-induced periodic surface structure (LIPSS) was prepared via femtosecond laser micro-processing. The low detection limit of glucose is 10-7 mol/L and, a good linear relationship between the glucose concentration and Raman intensity is found in the range between 1 × 10-7 and 1 × 10-3 mol/L. Moreover, we investigate SERS detection for glucose sensing in human urine samples, while the results are in good agreement with clinical results. The Letter provides a facile method for producing a structure-controlled SERS substrate to realize glucose detection, which is promising for long-term in vivo diagnostics.

UR - https://www.scopus.com/pages/publications/85111640234

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DO - 10.1364/OL.430044

M3 - 文章

C2 - 34329285

AN - SCOPUS:85111640234

SN - 0146-9592

VL - 46

SP - 3801

EP - 3804

JO - Optics Letters

JF - Optics Letters

IS - 15

ER -

Enhancing SERS detection on a biocompatible metallic substrate for diabetes diagnosing

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