@inproceedings{af7832bf12de4e9e8aafb68abf092365,
title = "Electrochemical aptasensor for L-histidine detection via self-cleavage of DNAzymes and amplification of end-truncated elongated tetrahexaheral gold nanocrystals",
abstract = "A sensitive aptamer-based signal-on sensor for real-time detection of L-histidine via selfcleavage of DNAzymes and amplification of elongated tetrahexaheral gold nanocrystals (endtruncated-ETHH-Au-NCs) is presented. The introduction of target L-histidine induced selfcleavage of DNAzymes on the end-truncated-ETHH-Au-NCs modified glassy carbon electrode (GCE) into the solution. The resulting change in electron transfer efficiency is readily measured by square wave voltammetry (SWV) at target L-histidine concentrations as low as 0.1 pM, the increase in the SWV peak current is linear with the concentration of L-histidine in the range from 0.1 pM to 0.1 μM. The fabricated aptasensor shows a high specificity for L-histidine which is not affected by the coexistence of other amino acids, and an excellent enantio-selectivity toward L-histidine was achieved.",
keywords = "Aptasensor, Electrochemistry, End-truncated-ETHH-Au-NCs, L-histidine, Self-cleavage",
author = "Zhengbo Chen and Xiaojiao Mu and Jing Li and Lidong Li and Lin Guo",
year = "2012",
doi = "10.4028/www.scientific.net/AMR.485.213",
language = "英语",
isbn = "9783037853740",
series = "Applied Mechanics and Materials",
publisher = "Trans Tech Publications Ltd",
pages = "213--216",
booktitle = "Advanced Research on Material Engineering and Its Application",
address = "瑞士",
note = "2012 2nd International Conference on Information Science, Automation and Material System, ISAM 2012 ; Conference date: 21-04-2012 Through 22-04-2012",
}