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DiffuX2CT: Diffusion Learning to Reconstruct CT Images from Biplanar X-Rays

  • Xuhui Liu
  • , Zhi Qiao
  • , Runkun Liu
  • , Hong Li
  • , Juan Zhang*
  • , Xiantong Zhen*
  • , Zhen Qian
  • , Baochang Zhang
  • *Corresponding author for this work
  • Beihang University
  • Central Research Institute
  • Zhongguancun Laboratory

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Computed tomography (CT) is widely utilized in clinical settings because it delivers detailed 3D images of the human body. However, performing CT scans is not always feasible due to radiation exposure and limitations in certain surgical environments. As an alternative, reconstructing CT images from ultra-sparse X-rays offers a valuable solution and has gained significant interest in scientific research and medical applications. However, it presents great challenges as it is inherently an ill-posed problem, often compromised by artifacts resulting from overlapping structures in X-ray images. In this paper, we propose DiffuX2CT, which models CT reconstruction from orthogonal biplanar X-rays as a conditional diffusion process. DiffuX2CT is established with a 3D global coherence denoising model with a new, implicit conditioning mechanism. We realize the conditioning mechanism by a newly designed tri-plane decoupling generator and an implicit neural decoder. By doing so, DiffuX2CT achieves structure-controllable reconstruction, which enables 3D structural information to be recovered from 2D X-rays, therefore producing faithful textures in CT images. As an extra contribution, we collect a real-world lumbar CT dataset, called LumbarV, as a new benchmark to verify the clinical significance and performance of CT reconstruction from X-rays. Extensive experiments on this dataset and three more publicly available datasets demonstrate the effectiveness of our proposal.

Original languageEnglish
Title of host publicationComputer Vision – ECCV 2024 - 18th European Conference, Proceedings
EditorsAleš Leonardis, Elisa Ricci, Stefan Roth, Olga Russakovsky, Torsten Sattler, Gül Varol
PublisherSpringer Science and Business Media Deutschland GmbH
Pages458-476
Number of pages19
ISBN (Print)9783031727740
DOIs
StatePublished - 2025
Event18th European Conference on Computer Vision, ECCV 2024 - Milan, Italy
Duration: 29 Sep 20244 Oct 2024

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume15101 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference18th European Conference on Computer Vision, ECCV 2024
Country/TerritoryItaly
CityMilan
Period29/09/244/10/24

Keywords

  • CT Reconstruction from Biplanar X-rays
  • Implicit Conditioning Mechanism
  • Tri-plane Representation

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