@inproceedings{be5e3ec79e3046ea97fdee76824af8cb,
title = "Depth-recognizable time-domain fluorescence molecular tomography in reflectance geometry",
abstract = "Utilizing reflective photons could circumvent the penetration limit of FMT, enabling reconstruction of fluorescence distribution near the surface regard less of the object size and extending its applications to surgical navigation and so on. Therefore, a time-domain reflective fluorescence molecular tomography (TD-rFMT) is proposed. The system excites and detects the emission light from the same angle within a field of view of 5 cm. Because the detected intensities of targets depend strongly on the depth, the reconstruction of targets in deep regions would be evidently affected. Therefore, a fluorescence yield reconstruction method with depth regularization and a weighted separation reconstruction strategy for lifetime are developed to enhance the performance for deep targets. Through simulations and phantom experiments, TD-rFMT is proved capable of reconstructing fluorescence distribution within a 2.5-cm depth with accurate reconstructed yield, lifetime, and target position(s).",
keywords = "Depth regularization, Fluorescence molecular tomography, Lifetime, Reflective geometry",
author = "Jiaju Cheng and Peng Zhang and Chuangjian Cai and Yang Gao and Jie Liu and Hui Hui and Jie Tian and Jianwen Luo",
note = "Publisher Copyright: {\textcopyright} 2021 SPIE.; Optics in Health Care and Biomedical Optics XI 2021 ; Conference date: 10-10-2021 Through 12-10-2021",
year = "2021",
doi = "10.1117/12.2602483",
language = "英语",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "SPIE",
editor = "Qingming Luo and Xingde Li and Ying Gu and Dan Zhu",
booktitle = "Optics in Health Care and Biomedical Optics XI",
address = "美国",
}