Degradation, hemolysis, and cytotoxicity of silane coatings on biodegradable magnesium alloy

X. N. Gu; H. M. Guo; F. Wang; Y. Lu; W. T. Lin; J. Li; Y. F. Zheng; Y. B. Fan

doi:10.1016/j.matlet.2017.01.136

Degradation, hemolysis, and cytotoxicity of silane coatings on biodegradable magnesium alloy

X. N. Gu^*
, H. M. Guo
, F. Wang
, Y. Lu
, W. T. Lin
, J. Li
, Y. F. Zheng
, Y. B. Fan

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

The major obstacle to the clinical use of magnesium alloys is their fast degradation behaviors. In the present study, the triethoxy(octyl)silane coatings were electrodeposited on magnesium alloy to improve the corrosion resistance and biocompatibility. The effects of the electrodeposition potential on the corrosion properties of the silane coatings were investigated. The resulted coatings were characterized by SEM, FTIR, surface hydrophobicity, in addition, the corrosion behaviors and biocompatibilities were also evaluated. The results indicated that the coatings deposited at −2.0 V were more corrosion resistant than the other two silane coatings. Furthermore, the silane coatings showed good biocompatibilities, as demonstrated by significant increased cell viability, reduced hemolysis and platelet adhesion.

Original language	English
Pages (from-to)	266-269
Number of pages	4
Journal	Materials Letters
Volume	193
DOIs	https://doi.org/10.1016/j.matlet.2017.01.136
State	Published - 15 Apr 2017

Keywords

Biocompatibility
Biomaterials
Coating
Corrosion
Magnesium alloys

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10.1016/j.matlet.2017.01.136

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title = "Degradation, hemolysis, and cytotoxicity of silane coatings on biodegradable magnesium alloy",

abstract = "The major obstacle to the clinical use of magnesium alloys is their fast degradation behaviors. In the present study, the triethoxy(octyl)silane coatings were electrodeposited on magnesium alloy to improve the corrosion resistance and biocompatibility. The effects of the electrodeposition potential on the corrosion properties of the silane coatings were investigated. The resulted coatings were characterized by SEM, FTIR, surface hydrophobicity, in addition, the corrosion behaviors and biocompatibilities were also evaluated. The results indicated that the coatings deposited at −2.0 V were more corrosion resistant than the other two silane coatings. Furthermore, the silane coatings showed good biocompatibilities, as demonstrated by significant increased cell viability, reduced hemolysis and platelet adhesion.",

keywords = "Biocompatibility, Biomaterials, Coating, Corrosion, Magnesium alloys",

author = "Gu, \{X. N.\} and Guo, \{H. M.\} and F. Wang and Y. Lu and Lin, \{W. T.\} and J. Li and Zheng, \{Y. F.\} and Fan, \{Y. B.\}",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

month = apr,

day = "15",

doi = "10.1016/j.matlet.2017.01.136",

language = "英语",

volume = "193",

pages = "266--269",

journal = "Materials Letters",

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TY - JOUR

T1 - Degradation, hemolysis, and cytotoxicity of silane coatings on biodegradable magnesium alloy

AU - Gu, X. N.

AU - Guo, H. M.

AU - Wang, F.

AU - Lu, Y.

AU - Lin, W. T.

AU - Li, J.

AU - Zheng, Y. F.

AU - Fan, Y. B.

PY - 2017/4/15

Y1 - 2017/4/15

N2 - The major obstacle to the clinical use of magnesium alloys is their fast degradation behaviors. In the present study, the triethoxy(octyl)silane coatings were electrodeposited on magnesium alloy to improve the corrosion resistance and biocompatibility. The effects of the electrodeposition potential on the corrosion properties of the silane coatings were investigated. The resulted coatings were characterized by SEM, FTIR, surface hydrophobicity, in addition, the corrosion behaviors and biocompatibilities were also evaluated. The results indicated that the coatings deposited at −2.0 V were more corrosion resistant than the other two silane coatings. Furthermore, the silane coatings showed good biocompatibilities, as demonstrated by significant increased cell viability, reduced hemolysis and platelet adhesion.

AB - The major obstacle to the clinical use of magnesium alloys is their fast degradation behaviors. In the present study, the triethoxy(octyl)silane coatings were electrodeposited on magnesium alloy to improve the corrosion resistance and biocompatibility. The effects of the electrodeposition potential on the corrosion properties of the silane coatings were investigated. The resulted coatings were characterized by SEM, FTIR, surface hydrophobicity, in addition, the corrosion behaviors and biocompatibilities were also evaluated. The results indicated that the coatings deposited at −2.0 V were more corrosion resistant than the other two silane coatings. Furthermore, the silane coatings showed good biocompatibilities, as demonstrated by significant increased cell viability, reduced hemolysis and platelet adhesion.

KW - Biocompatibility

KW - Biomaterials

KW - Coating

KW - Corrosion

KW - Magnesium alloys

UR - https://www.scopus.com/pages/publications/85012201675

U2 - 10.1016/j.matlet.2017.01.136

DO - 10.1016/j.matlet.2017.01.136

M3 - 文章

AN - SCOPUS:85012201675

SN - 0167-577X

VL - 193

SP - 266

EP - 269

JO - Materials Letters

JF - Materials Letters

ER -

Degradation, hemolysis, and cytotoxicity of silane coatings on biodegradable magnesium alloy

Abstract

Keywords

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