Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models

Zeyu Zhang; Hongbo Guo; Zhenhua Hu; Jie Tian

doi:10.1109/NSSMIC.2017.8533041

Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models

Zeyu Zhang
, Hongbo Guo
, Zhenhua Hu
, Jie Tian

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Cerenkov luminescence imaging (CLI) proved as a promising approach for molecular imaging of cancer. However, most of the conventional optical detection devices fail to acquire CL images since the Cerenkov luminescence intensity is extraordinarily weak. Recently, endoscopic CLI (ECLI) was proposed as a highly attractive approach for tumor detection and surgery. In this study, an ECLI system was constructed with a novel cooling solution, which can effectively reduce the system thermal noise and dramatically improve the imaging sensitivity. The developed ECLI system was further explored for imageguided surgery of hepatocellular carcinoma (HCC) on mice models.

Original language	English
Title of host publication	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781538622827
DOIs	https://doi.org/10.1109/NSSMIC.2017.8533041
State	Published - 12 Nov 2018
Externally published	Yes
Event	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Atlanta, United States Duration: 21 Oct 2017 → 28 Oct 2017

Publication series

Name	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings

Conference

Conference	2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017
Country/Territory	United States
City	Atlanta
Period	21/10/17 → 28/10/17

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cerenkov luminescence imaging (CLI)
Endoscopy system
image-guided tumor resection

Access to Document

10.1109/NSSMIC.2017.8533041

Cite this

Zhang, Z., Guo, H., Hu, Z., & Tian, J. (2018). Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models. In 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings Article 8533041 (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NSSMIC.2017.8533041

Zhang, Zeyu ; Guo, Hongbo ; Hu, Zhenhua et al. / Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models. 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings).

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title = "Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models",

abstract = "Cerenkov luminescence imaging (CLI) proved as a promising approach for molecular imaging of cancer. However, most of the conventional optical detection devices fail to acquire CL images since the Cerenkov luminescence intensity is extraordinarily weak. Recently, endoscopic CLI (ECLI) was proposed as a highly attractive approach for tumor detection and surgery. In this study, an ECLI system was constructed with a novel cooling solution, which can effectively reduce the system thermal noise and dramatically improve the imaging sensitivity. The developed ECLI system was further explored for imageguided surgery of hepatocellular carcinoma (HCC) on mice models.",

keywords = "Cerenkov luminescence imaging (CLI), Endoscopy system, image-guided tumor resection",

author = "Zeyu Zhang and Hongbo Guo and Zhenhua Hu and Jie Tian",

note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 ; Conference date: 21-10-2017 Through 28-10-2017",

year = "2018",

month = nov,

day = "12",

doi = "10.1109/NSSMIC.2017.8533041",

language = "英语",

series = "2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

booktitle = "2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings",

address = "美国",

}

Zhang, Z, Guo, H, Hu, Z & Tian, J 2018, Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models. in 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings., 8533041, 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings, Institute of Electrical and Electronics Engineers Inc., 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017, Atlanta, United States, 21/10/17. https://doi.org/10.1109/NSSMIC.2017.8533041

Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models. / Zhang, Zeyu; Guo, Hongbo; Hu, Zhenhua et al.
2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc., 2018. 8533041 (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models

AU - Zhang, Zeyu

AU - Guo, Hongbo

AU - Hu, Zhenhua

AU - Tian, Jie

PY - 2018/11/12

Y1 - 2018/11/12

N2 - Cerenkov luminescence imaging (CLI) proved as a promising approach for molecular imaging of cancer. However, most of the conventional optical detection devices fail to acquire CL images since the Cerenkov luminescence intensity is extraordinarily weak. Recently, endoscopic CLI (ECLI) was proposed as a highly attractive approach for tumor detection and surgery. In this study, an ECLI system was constructed with a novel cooling solution, which can effectively reduce the system thermal noise and dramatically improve the imaging sensitivity. The developed ECLI system was further explored for imageguided surgery of hepatocellular carcinoma (HCC) on mice models.

AB - Cerenkov luminescence imaging (CLI) proved as a promising approach for molecular imaging of cancer. However, most of the conventional optical detection devices fail to acquire CL images since the Cerenkov luminescence intensity is extraordinarily weak. Recently, endoscopic CLI (ECLI) was proposed as a highly attractive approach for tumor detection and surgery. In this study, an ECLI system was constructed with a novel cooling solution, which can effectively reduce the system thermal noise and dramatically improve the imaging sensitivity. The developed ECLI system was further explored for imageguided surgery of hepatocellular carcinoma (HCC) on mice models.

KW - Cerenkov luminescence imaging (CLI)

KW - Endoscopy system

KW - image-guided tumor resection

UR - https://www.scopus.com/pages/publications/85058486239

U2 - 10.1109/NSSMIC.2017.8533041

DO - 10.1109/NSSMIC.2017.8533041

M3 - 会议稿件

AN - SCOPUS:85058486239

T3 - 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings

BT - 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017

Y2 - 21 October 2017 through 28 October 2017

ER -

Zhang Z, Guo H, Hu Z, Tian J. Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models. In 2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings. Institute of Electrical and Electronics Engineers Inc. 2018. 8533041. (2017 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2017 - Conference Proceedings). doi: 10.1109/NSSMIC.2017.8533041

Construction of a Novel Endoscopic Cerenkov Luminescence Imaging System for Image-Guided Resection of Hepatocellular Carcinoma on Mice Models

Abstract

Publication series

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UN SDGs

Keywords

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