Computational model describing osteoporotic process of cancellous bone

  • Hao Zhang*
  • , Xing Hua Zhu
  • , Lin Yang
  • , He Gong
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

To quantify the Osteoporotic process of the cancellous bone, based on the bone functional adaptation and Frost's mechanostat theory, a computational model with time history was put forward following the physiological process of bone remodeling to simulate the osteoporosis caused by disuse. The effects of peak bone mass on Osteoporotic process of cancellous bone were discussed. The results show the simulated Osteoporotic process caused by disuse was similar to the real physiological process, and higher peak bone mass can postpone the occurrence of osteoporosis.

Original languageEnglish
Pages (from-to)334-338
Number of pages5
JournalJilin Daxue Xuebao (Gongxueban)/Journal of Jilin University (Engineering and Technology Edition)
Volume35
Issue number3
StatePublished - May 2005
Externally publishedYes

Keywords

  • Basic multicellular unit
  • Biomechanics
  • Bone functional adaptation
  • Bone remodeling
  • Osteoporosis
  • Peak bone mass

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