TY - GEN
T1 - CGCA-KAN
T2 - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
AU - Zhang, Peng
AU - Wu, Yida
AU - Liu, Chen
AU - Zhao, Heyang
AU - Liu, Xingyu
AU - Liu, Zeyu
AU - Zhang, Guanglei
AU - Wang, Wenjian
N1 - Publisher Copyright:
© 2025 IEEE.
PY - 2025
Y1 - 2025
N2 - Accurate medical image segmentation relies on collaborative modeling of local details and global semantics, especially in small-volume structures, blurred boundaries, and fine-grained anatomical regions under low signal-to-noise conditions. However, existing transformer-based methods typically suffer from feature redundancy problems caused by inaccurate attention mechanism focus and nonlinear modeling defects caused by insufficient expression ability of feedforward networks, which leads to attention bias and nonlinear modeling bias, and ultimately degrades segmentation performance. To address these challenges, we propose CGCA-KAN, a novel transformer-based framework that employs a collaborative correction mechanism (CCM) to jointly mitigate attention bias and nonlinear modeling bias. Specifically, we introduce a cluster-aware self-attention module (CASAM) to mitigate attention bias by refining semantic focus and suppressing redundancy through token group compression, thereby enhancing attention to small-volume structures. Additionally, we design a Kolmogorov-Arnold Network enhanced feedforward network (KAN-EFFN) to mitigate nonlinear modeling bias through adaptive nonlinear transformations, thereby improving the model's ability to delineate blurred boundaries. Extensive experiments on LiTS2017, Synapse, and BraTS2020 datasets demonstrate state-of-the-art performance in fine-grained segmentation of ambiguous lesions in the liver, complex structures of multiple organs, and brain tumors. Our results highlight CGCA-KAN as a promising solution for addressing modeling biases in medical image segmentation.
AB - Accurate medical image segmentation relies on collaborative modeling of local details and global semantics, especially in small-volume structures, blurred boundaries, and fine-grained anatomical regions under low signal-to-noise conditions. However, existing transformer-based methods typically suffer from feature redundancy problems caused by inaccurate attention mechanism focus and nonlinear modeling defects caused by insufficient expression ability of feedforward networks, which leads to attention bias and nonlinear modeling bias, and ultimately degrades segmentation performance. To address these challenges, we propose CGCA-KAN, a novel transformer-based framework that employs a collaborative correction mechanism (CCM) to jointly mitigate attention bias and nonlinear modeling bias. Specifically, we introduce a cluster-aware self-attention module (CASAM) to mitigate attention bias by refining semantic focus and suppressing redundancy through token group compression, thereby enhancing attention to small-volume structures. Additionally, we design a Kolmogorov-Arnold Network enhanced feedforward network (KAN-EFFN) to mitigate nonlinear modeling bias through adaptive nonlinear transformations, thereby improving the model's ability to delineate blurred boundaries. Extensive experiments on LiTS2017, Synapse, and BraTS2020 datasets demonstrate state-of-the-art performance in fine-grained segmentation of ambiguous lesions in the liver, complex structures of multiple organs, and brain tumors. Our results highlight CGCA-KAN as a promising solution for addressing modeling biases in medical image segmentation.
KW - Cluster-Aware Attention
KW - Collaborative Correction Mechanism
KW - Kol-mogorov-Arnold Network
KW - Medical Image Segmentation
KW - Transformer
UR - https://www.scopus.com/pages/publications/105033601866
U2 - 10.1109/BIBM66473.2025.11356868
DO - 10.1109/BIBM66473.2025.11356868
M3 - 会议稿件
AN - SCOPUS:105033601866
T3 - Proceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
SP - 4408
EP - 4413
BT - Proceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
A2 - Liu, Juan
A2 - Huang, Jingshan
A2 - Wang, Xiaowo
A2 - Zhang, Fa
A2 - Zou, Xiufen
A2 - Tian, Tian
A2 - Hu, Xiaohua
A2 - Hu, Bin
A2 - Xiong, Yi
PB - Institute of Electrical and Electronics Engineers Inc.
Y2 - 15 December 2025 through 18 December 2025
ER -