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CGCA-KAN: Correction-Guided Cluster-Aware Attention and KAN Enhanced Architecture for Medical Image Segmentation

  • Peng Zhang*
  • , Yida Wu*
  • , Chen Liu
  • , Heyang Zhao
  • , Xingyu Liu
  • , Zeyu Liu
  • , Guanglei Zhang
  • , Wenjian Wang
  • *Corresponding author for this work
  • Shanxi University
  • Beihang University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Accurate medical image segmentation relies on collaborative modeling of local details and global semantics, especially in small-volume structures, blurred boundaries, and fine-grained anatomical regions under low signal-to-noise conditions. However, existing transformer-based methods typically suffer from feature redundancy problems caused by inaccurate attention mechanism focus and nonlinear modeling defects caused by insufficient expression ability of feedforward networks, which leads to attention bias and nonlinear modeling bias, and ultimately degrades segmentation performance. To address these challenges, we propose CGCA-KAN, a novel transformer-based framework that employs a collaborative correction mechanism (CCM) to jointly mitigate attention bias and nonlinear modeling bias. Specifically, we introduce a cluster-aware self-attention module (CASAM) to mitigate attention bias by refining semantic focus and suppressing redundancy through token group compression, thereby enhancing attention to small-volume structures. Additionally, we design a Kolmogorov-Arnold Network enhanced feedforward network (KAN-EFFN) to mitigate nonlinear modeling bias through adaptive nonlinear transformations, thereby improving the model's ability to delineate blurred boundaries. Extensive experiments on LiTS2017, Synapse, and BraTS2020 datasets demonstrate state-of-the-art performance in fine-grained segmentation of ambiguous lesions in the liver, complex structures of multiple organs, and brain tumors. Our results highlight CGCA-KAN as a promising solution for addressing modeling biases in medical image segmentation.

Original languageEnglish
Title of host publicationProceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
EditorsJuan Liu, Jingshan Huang, Xiaowo Wang, Fa Zhang, Xiufen Zou, Tian Tian, Xiaohua Hu, Bin Hu, Yi Xiong
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages4408-4413
Number of pages6
ISBN (Electronic)9798331515577
DOIs
StatePublished - 2025
Event2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025 - Wuhan, China
Duration: 15 Dec 202518 Dec 2025

Publication series

NameProceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025

Conference

Conference2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
Country/TerritoryChina
CityWuhan
Period15/12/2518/12/25

Keywords

  • Cluster-Aware Attention
  • Collaborative Correction Mechanism
  • Kol-mogorov-Arnold Network
  • Medical Image Segmentation
  • Transformer

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