Cell mechanics in early vertebrate development: Yap mechanotransduction controls notochord formation and neural tube patterning

Zheng Guo; Jing Du

doi:10.1016/j.mbm.2023.100029

Cell mechanics in early vertebrate development: Yap mechanotransduction controls notochord formation and neural tube patterning

Zheng Guo
, Jing Du^*

^*Corresponding author for this work

School of Biological Science and Medical Engineering

Beihang University

Research output: Contribution to journal › Comment/debate

Abstract

A recent study published in Science Advances¹ showed the influence of Yap on notochord formation and NT (neural tube) patterning in vertebrate embryonic development, and conducted an in-depth study from the perspective of biomechanical signal mechanotransduction. In addition, this study also explored the possible complex interaction between mechanical signals and gene expression. Together, this study provides new insights into the development mechanism of early vertebrate embryos.

Original language	English
Article number	100029
Journal	Mechanobiology in Medicine
Volume	1
Issue number	2
DOIs	https://doi.org/10.1016/j.mbm.2023.100029
State	Published - Dec 2023

Keywords

Embryonic development
Mechanotransduction
Neural tube
Notochord
Taz
Yap

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10.1016/j.mbm.2023.100029

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title = "Cell mechanics in early vertebrate development: Yap mechanotransduction controls notochord formation and neural tube patterning",

abstract = "A recent study published in Science Advances1 showed the influence of Yap on notochord formation and NT (neural tube) patterning in vertebrate embryonic development, and conducted an in-depth study from the perspective of biomechanical signal mechanotransduction. In addition, this study also explored the possible complex interaction between mechanical signals and gene expression. Together, this study provides new insights into the development mechanism of early vertebrate embryos.",

keywords = "Embryonic development, Mechanotransduction, Neural tube, Notochord, Taz, Yap",

author = "Zheng Guo and Jing Du",

note = "Publisher Copyright: {\textcopyright} 2023 The Authors",

year = "2023",

month = dec,

doi = "10.1016/j.mbm.2023.100029",

language = "英语",

volume = "1",

journal = "Mechanobiology in Medicine",

issn = "2949-9070",

publisher = "Elsevier B.V.",

number = "2",

}

TY - JOUR

T1 - Cell mechanics in early vertebrate development

T2 - Yap mechanotransduction controls notochord formation and neural tube patterning

AU - Guo, Zheng

AU - Du, Jing

PY - 2023/12

Y1 - 2023/12

N2 - A recent study published in Science Advances1 showed the influence of Yap on notochord formation and NT (neural tube) patterning in vertebrate embryonic development, and conducted an in-depth study from the perspective of biomechanical signal mechanotransduction. In addition, this study also explored the possible complex interaction between mechanical signals and gene expression. Together, this study provides new insights into the development mechanism of early vertebrate embryos.

AB - A recent study published in Science Advances1 showed the influence of Yap on notochord formation and NT (neural tube) patterning in vertebrate embryonic development, and conducted an in-depth study from the perspective of biomechanical signal mechanotransduction. In addition, this study also explored the possible complex interaction between mechanical signals and gene expression. Together, this study provides new insights into the development mechanism of early vertebrate embryos.

KW - Embryonic development

KW - Mechanotransduction

KW - Neural tube

KW - Notochord

KW - Taz

KW - Yap

UR - https://www.scopus.com/pages/publications/85206486353

U2 - 10.1016/j.mbm.2023.100029

DO - 10.1016/j.mbm.2023.100029

M3 - 评论/辩论

AN - SCOPUS:85206486353

SN - 2949-9070

VL - 1

JO - Mechanobiology in Medicine

JF - Mechanobiology in Medicine

IS - 2

M1 - 100029

ER -

Cell mechanics in early vertebrate development: Yap mechanotransduction controls notochord formation and neural tube patterning

Abstract

Keywords

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