Cell Focusing and Rotation by a Planar Optoelectronic Tweezers

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Optoelectronic tweezers (OETs) based on dielectrophoresis (DEP) force is a valuable tool for the manipulation of particles and cells. However, DEP-based methods that can measure the electrical parameters are always preformed on static metal electrode DEP systems. Here, we present a partitioned single-sided OET chip that combines an OET system and microfluidic channel. Unlike classical sandwich-structure OET chip, the single-sided chip is close to the metal electrode DEP system but can switch functions easily. Numerical simulations are studied to analyze the electric field on a microfluidic chip and provide data for characterizing cell electric properties. The focusing and electro-rotation are successfully realized by partitioned multi-signal OET system. By analyzing the rotation speed, some specific electric parameters of Raw cells are characterized. The work has laid a foundation for OET-based single-sided chip fabrication and experiment validation.

Original languageEnglish
Title of host publicationProceedings of MARSS 2022 - 5th International Conference on Manipulation, Automation, and Robotics at Small Scales
EditorsSinan Haliyo, Mokrane Boudaoud, Eric Diller, Xinyu Liu, Yu Sun, Sergej Fatikow
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665459730
DOIs
StatePublished - 2022
Event5th International Conference on Manipulation, Automation, and Robotics at Small Scales, MARSS 2022 - Toronto, Canada
Duration: 25 Jul 202229 Jul 2022

Publication series

NameProceedings of MARSS 2022 - 5th International Conference on Manipulation, Automation, and Robotics at Small Scales

Conference

Conference5th International Conference on Manipulation, Automation, and Robotics at Small Scales, MARSS 2022
Country/TerritoryCanada
CityToronto
Period25/07/2229/07/22

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