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An anatomical mouse model for multimodal molecular imaging

  • Xing Zhang*
  • , Jie Tian
  • , Jinchao Feng
  • , Shouping Zhu
  • , Guorui Yan
  • *Corresponding author for this work
  • Chinese Academy of Sciences

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In order to evaluate and improve multimodal molecular imaging technology, a three-dimensional anatomical model of a BALB/c mouse was developed based on micro-CT imaging with a liver-specific contrast agent Fenestra LC. By using image processing and interactive segmentation methods, we delineated some primary organs and tissues, including the skin, skeleton, muscle, heart, lung, liver and spleen. Finally, cone-beam x-ray CT and bioluminescence tomography simulation experiments demonstrate the availability and flexibility of the proposed mouse model.

Original languageEnglish
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages5817-5820
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - 2009
Externally publishedYes
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: 2 Sep 20096 Sep 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Conference

Conference31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Country/TerritoryUnited States
CityMinneapolis, MN
Period2/09/096/09/09

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