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Algebraic analysis of bifurcation and limit cycles for biological systems

  • Laboratoire d'Informatique de Paris 6

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this paper, we show how to analyze bifurcation and limit cycles for biological systems by using an algebraic approach based on triangular decomposition, Gröbner bases, discriminant varieties, real solution classification, and quantifier elimination by partial CAD. The analysis of bifurcation and limit cycles for a concrete two-dimensional system, the self-assembling micelle system with chemical sinks, is presented in detail. It is proved that this system may have a focus of order 3, from which three limit cycles can be constructed by small perturbation. The applicability of our approach is further illustrated by the construction of limit cycles for a two-dimensional Kolmogorov prey-predator system and a three-dimensional Lotka-Volterra system.

Original languageEnglish
Title of host publicationAlgebraic Biology - Third International Conference, AB 2008, Proceedings
Pages156-171
Number of pages16
DOIs
StatePublished - 2008
Event3rd International Conference on Algebraic Biology, AB 2008 - Castle of Hagenberg, Austria
Duration: 31 Jul 20082 Aug 2008

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume5147 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference3rd International Conference on Algebraic Biology, AB 2008
Country/TerritoryAustria
CityCastle of Hagenberg
Period31/07/082/08/08

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