ABCD Neurocognitive Prediction Challenge 2019: Predicting Individual Residual Fluid Intelligence Scores from Cortical Grey Matter Morphology

  • Neil P. Oxtoby*
  • , Fabio S. Ferreira
  • , Agoston Mihalik
  • , Tong Wu
  • , Mikael Brudfors
  • , Hongxiang Lin
  • , Anita Rau
  • , Stefano B. Blumberg
  • , Maria Robu
  • , Cemre Zor
  • , Maira Tariq
  • , Mar Estarellas Garcia
  • , Baris Kanber
  • , Daniil I. Nikitichev
  • , Janaina Mourão-Miranda
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We predicted fluid intelligence from T1-weighted MRI data available as part of the ABCD NP Challenge 2019, using morphological similarity of grey-matter regions across the cortex. Individual structural covariance networks (SCN) were abstracted into graph-theory metrics averaged over nodes across the brain and in data-driven communities/modules. Metrics included degree, path length, clustering coefficient, centrality, rich club coefficient, and small-worldness. These features derived from the training set were used to build various regression models for predicting residual fluid intelligence scores, with performance evaluated both using cross-validation within the training set and using the held-out validation set. Our predictions on the test set were generated with a support vector regression model trained on the training set. We found minimal improvement over predicting a zero residual fluid intelligence score across the sample population, implying that structural covariance networks calculated from T1-weighted MR imaging data provide little information about residual fluid intelligence.

Original languageEnglish
Title of host publicationAdolescent Brain Cognitive Development Neurocognitive Prediction - 1st Challenge, ABCD-NP 2019, held in Conjunction with MICCAI 2019, Proceedings
EditorsKilian M. Pohl, Ehsan Adeli, Wesley K. Thompson, Marius George Linguraru
PublisherSpringer
Pages114-123
Number of pages10
ISBN (Print)9783030319007
DOIs
StatePublished - 2019
Externally publishedYes
Event1st Challenge in Adolescent Brain Cognitive Development Neurocognitive Prediction, ABCD-NP 2019, held in conjunction with the 22nd International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2019 - Shenzhen, China
Duration: 13 Oct 201913 Oct 2019

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume11791 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference1st Challenge in Adolescent Brain Cognitive Development Neurocognitive Prediction, ABCD-NP 2019, held in conjunction with the 22nd International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2019
Country/TerritoryChina
CityShenzhen
Period13/10/1913/10/19

Keywords

  • Fluid intelligence
  • Graph theory features
  • MRI
  • Structural covariance networks
  • Support vector regression

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