TY - GEN
T1 - A Study on the Generation of Single Cell Droplets via the Combination of Lateral-Field Optoelectronic Tweezers and Electrowetting-on-Dielectric
AU - Zhao, Jiawei
AU - Huang, Shunxiao
AU - Xiong, Hongyi
AU - Gan, Chunyuan
AU - Ye, Jingwen
AU - Niu, Wenyan
AU - Feng, Lin
N1 - Publisher Copyright:
© 2025 IEEE.
PY - 2025
Y1 - 2025
N2 - Microfluidic technology is currently a popular approach in the field of single-cell research, which is used to reveal the heterogeneity among cells. However, most of the existing microfluidic technologies for single-cell research lack the ability to control the microenvironment of single cells after isolating them. In this work, a technology that combines lateral-field optoelectronic tweezers (LOET) with electrowetting-on-dielectric (EWOD) is used to separate cells into single cells and then encapsulate each single cell within an individual droplet, generating single-cell droplets. More importantly, it also enables the control of the microenvironment of the separated single cells. The driving control of the single - cell droplets is achieved through the EWOD, which has good application prospects in the field of single- cell research.
AB - Microfluidic technology is currently a popular approach in the field of single-cell research, which is used to reveal the heterogeneity among cells. However, most of the existing microfluidic technologies for single-cell research lack the ability to control the microenvironment of single cells after isolating them. In this work, a technology that combines lateral-field optoelectronic tweezers (LOET) with electrowetting-on-dielectric (EWOD) is used to separate cells into single cells and then encapsulate each single cell within an individual droplet, generating single-cell droplets. More importantly, it also enables the control of the microenvironment of the separated single cells. The driving control of the single - cell droplets is achieved through the EWOD, which has good application prospects in the field of single- cell research.
UR - https://www.scopus.com/pages/publications/105029932043
U2 - 10.1109/IROS60139.2025.11247135
DO - 10.1109/IROS60139.2025.11247135
M3 - 会议稿件
AN - SCOPUS:105029932043
T3 - IEEE International Conference on Intelligent Robots and Systems
SP - 283
EP - 288
BT - IROS 2025 - 2025 IEEE/RSJ International Conference on Intelligent Robots and Systems, Conference Proceedings
A2 - Laugier, Christian
A2 - Renzaglia, Alessandro
A2 - Atanasov, Nikolay
A2 - Birchfield, Stan
A2 - Cielniak, Grzegorz
A2 - De Mattos, Leonardo
A2 - Fiorini, Laura
A2 - Giguere, Philippe
A2 - Hashimoto, Kenji
A2 - Ibanez-Guzman, Javier
A2 - Kamegawa, Tetsushi
A2 - Lee, Jinoh
A2 - Loianno, Giuseppe
A2 - Luck, Kevin
A2 - Maruyama, Hisataka
A2 - Martinet, Philippe
A2 - Moradi, Hadi
A2 - Nunes, Urbano
A2 - Pettre, Julien
A2 - Pretto, Alberto
A2 - Ranzani, Tommaso
A2 - Ronnau, Arne
A2 - Rossi, Silvia
A2 - Rouse, Elliott
A2 - Ruggiero, Fabio
A2 - Simonin, Olivier
A2 - Wang, Danwei
A2 - Yang, Ming
A2 - Yoshida, Eiichi
A2 - Zhao, Huijing
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2025 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2025
Y2 - 19 October 2025 through 25 October 2025
ER -