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A preliminary study on metabolism modelling with capillary

  • Tsinghua University

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Substances transport and metabolism are essential for the maintenance of life. Some compartment models were proposed to describe the substances transport and metabolism in human body. However, they neglected the functions of capillary and could not show the effects of circulatory system. Capillary plays an important role in substances transport. In this paper, a novel mathematical model is presented for substances transport and metabolism. This model consists of two parts: one is substances transporting through capillary by Fick's conservation law; the other one uses a compartment model to describe the metabolism in tissue. This model is proved to be successful by numerical experimentation for brain.

Original languageEnglish
Title of host publication6th IFAC Symposium on Modeling and Control in Biomedical Systems, MCBMS 2006
PublisherIFAC Secretariat
Pages411-416
Number of pages6
EditionPART 1
ISBN (Print)9783902661180
DOIs
StatePublished - 2006
Externally publishedYes

Publication series

NameIFAC Proceedings Volumes (IFAC-PapersOnline)
NumberPART 1
Volume6
ISSN (Print)1474-6670

Keywords

  • Computer tomography
  • Numerical simulation
  • Parameter estimation
  • Permeability
  • Physiological model

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