A flexible graphene aptameric nanosensor for detection of TNF-¢

  • Zhuang Hao*
  • , Yibo Zhu
  • , Yijun Li
  • , Xuejun Wang
  • , Xuezeng Zhao
  • , Qiao Lin
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

We present a flexible graphene aptameric nanosensor, which can work properly under different bending radii, for rapid, direct, highly sensitive and label-free detection of TNF-α in physiologically relevant levels. The nanosensor is configured as an electrolyte-gated graphene field-effect transistor (GFET) and fabricated on a SiO2 covered polyethylene naphthalate (PEN) substrate. The detection is enabled by the affinity binding between TNF-α and graphene surface immobilized aptamer VR11. We characterized our flexible nanosensor with multiple TNF-α concentrations ranging from 5 nM to 500 nM under different bending radii.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages483-484
Number of pages2
ISBN (Electronic)9780692941836
StatePublished - 2020
Externally publishedYes
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: 22 Oct 201726 Oct 2017

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
Country/TerritoryUnited States
CitySavannah
Period22/10/1726/10/17

Keywords

  • Aptamer
  • Flexible nanosensor
  • Graphene
  • TNF-α

Fingerprint

Dive into the research topics of 'A flexible graphene aptameric nanosensor for detection of TNF-¢'. Together they form a unique fingerprint.

Cite this