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胞 质 分 裂 阻 滞 微 核 自 动 化 分 析 技 术 的 研 究 进 展

Translated title of the contribution: Research progress of automated micronucleus analysis technology for cytokinesis arrest
  • Xiang Shen
  • , Ying Chen
  • , Zhanbo Wen
  • , Jinlin Zheng
  • , Zhenggan Zhou*
  • *Corresponding author for this work
  • Beihang University
  • Academy of Military Medical Science China
  • Ltd.

Research output: Contribution to journalArticlepeer-review

Abstract

In the field of radiation biological dose estimation, cytokinesis-blocked micronucleus analysis (CBMN method) is the best internationally recognized estimation approach, excluding chromosomal aberrations. To overcome the limitations of the artificial CBMN method, namely the large amount of time and labor required for its execution, automated methods are being widely explored to detect binuclear cell micronuclei. This study involves an analysis of the relevant literature on an international level and an inspection and summary of the research on CBMN automated analysis so as to fully describe the current research progress and characteristics thereof. On this basis, future development trends of CBMN automated analysis can be predicted to provide useful references for researchers in related fields.

Translated title of the contributionResearch progress of automated micronucleus analysis technology for cytokinesis arrest
Original languageChinese (Traditional)
Article number030101
JournalFushe Yanjiu yu Fushe Gongyi Xuebao/Journal of Radiation Research and Radiation Processing
Volume39
Issue number3
DOIs
StatePublished - 20 Jun 2021

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